@proceedings {48,
	title = {Towards large-scale, high resolution maps of object selectivity in inferior temporal cortex},
	journal = {Computation and Systems Neuroscience (COSYNE)},
	year = {2010},
	month = {02/2010},
	address = {Salt Lake City, Utah, USA},
	abstract = {<p>Inferior temporal cortex (IT) has been shown to have large-scale (mm to cm) maps of object category selectivity as well as small-scale (sub-millimeter) organization for object features.\&nbsp; These two scales of spatial organization have yet to be linked because they were measured using different techniques (fMRI, optical imaging, and local electrophysiology), each with their own limitations.\&nbsp; For example, fMRI has poor spatial resolution while optical imaging has higher resolution at the expense of a narrow field of view of only surface-accessible cortex.\&nbsp; Given that much of IT lies inside a major cortical sulcus or at the skull base, what is needed is a method that can access the whole of IT with high resolution.\&nbsp; Microelectrode based mapping has such potential: electrodes can reach almost anywhere in IT (high spatial coverage) and record from single cells (high spatial resolution).\&nbsp;This potential has not yet been realized because of the difficulty of precisely localizing and co-registering many electrode recordings in vivo.\&nbsp; Methods such as histological reconstruction of lesion sites or MRI visualization of electrodes are post-hoc and can introduce additional spatial errors.\&nbsp; Here, we have adopted a microfocal stereo x-ray system for localizing electrodes that can be used at an unlimited number of sites and operates virtually in real-time (Cox et al., J. Neurophys. 2008).\&nbsp; We have used this system to construct broad scale maps of object category selectivity in IT for comparison to fMRI-based maps.\&nbsp; We found a weak but significant correspondence between physiology and fMRI maps collected in the same animal, and this correspondence improved substantially when MUA and LFP signals were smoothed (~3-5 mm) to broader scales suggesting the spatial low pass nature of fMRI.\&nbsp; Transformations other than spatial smoothing such as dividing the LFP into power in different frequency bands did not produce noticeable improvement in map correspondence.<br />
\&nbsp;</p>
},
	doi = {10.3389/conf.fnins.2010.03.00154},
	url = {https://www.frontiersin.org/Community/AbstractDetails.aspx?ABS_DOI=10.3389/conf.fnins.2010.03.00154\&eid=770\&sname=computational_and_systems_neur},
	author = {Issa, Elias B. and Papanastassiou, A. M. and Andken, BB and DiCarlo, James J.}
}
@proceedings {66,
	title = {A systematic exploration of the relationship of fMRI signals and neuronal activity in the primate temporal lobe},
	journal = {Society for Neuroscience},
	year = {2009},
	month = {11/2009},
	publisher = {SFN},
	address = {Washington, DC, USA},
	author = {Papanastassiou, A. M. and Op de Beeck, H. P. and Andken, BB and DiCarlo, James J.}
}
