@article {82,
	title = {Discrimination Training Alters Object Representations in Human Extrastriate Cortex},
	journal = {Journal of Neuroscience},
	volume = {26},
	year = {2006},
	month = {2006},
	pages = {13025 - 13036},
	abstract = {<p>Visual object recognition relies critically on learning. However, little is known about the effect of object learning in human visual cortex, and in particular how the spatial distribution of training effects relates to the distribution of object and face selectivity across the cortex before training. We scanned human subjects with high-resolution functional magnetic resonance imaging {(fMRI)} while they viewed novel object classes, both before and after extensive training to discriminate between exemplars within one of these object classes. Training increased the strength of the response in visual cortex to trained objects compared with untrained objects. However, training did not simply induce a uniform increase in the response to trained objects: the magnitude of this training effect varied substantially across subregions of extrastriate cortex, with some showing a twofold increase in response to trained objects and others (including the right fusiform face area) showing no significant effect of training. Furthermore, the spatial distribution of training effects could not be predicted from the spatial distribution of either pretrained responses or face selectivity. Instead, training changed the spatial distribution of activity across the cortex. These findings support a dynamic view of the ventral visual pathway in which the cortical representation of an object category is continuously modulated by experience.</p>
},
	issn = {0270-6474},
	doi = {10.1523/JNEUROSCI.2481-06.2006},
	url = {http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.2481-06.2006},
	author = {Op de Beeck, H. P. and Baker, C. I. and DiCarlo, J. J. and Kanwisher, N. G.}
}
